> [[CVD mortality negatively impact economic growth, only if income levels are sufficiently high to be impacted]]. From the sub-sample of middle and low-income countries, the CVD mortality does not have a significant relationship with economic growth, with several caveat: one, the data quality is considerably worse. Two, CVD have only been emerging quite strongly in the later part of this period in developing countries. # Summary We assess the impact of cardiovascular disease (CVD) mortality on economic growth, using a dynamic panel growth regression framework taking into account potential endogeneity problems. In the worldwide sample we detect a non-linear influence of working age CVD mortality rates on growth across the per capita income scale. Splitting the sample (according to the resulting income threshold) into low- and middle-income countries, and high-income countries, we find a robust negative contribution of increasing CVD mortality rates on subsequent five-year growth rates in the latter sample. Not too surprisingly, we find no significant impact in the low- and middle-income country sample. # Result We find a significant CVD mortality rate at working age (in high-income countries). Finally, we investigate whether the CVD variable really does have the opposite sign in the sub-sample of middle and low-income countries (results not reported, but available on request). However, ==we find that no significant relationship exists in this sub-sample==. One reason may be that data quality is considerably worse for low-income countries, yielding an attenuation bias. More likely, however, ==CVD mortality is not prevalent to the same extent as in high-income countries and therefore not an important growth determinant during our sample period. Hence, any negative impact of CVD on economic growth is only significant if income levels are sufficiently high==. # Conclusion 1. The paper analyze the impact of CVD on economic growth, with regression framework for the time period 1960-2000. 2. It is not entirely surprising that CVDs have no statistically significant role in explaining growth differences within poor countries, because CVDs have only been emerging quite strongly in the later part of this period in developing countries. 3. In fact, it should serve as a precaution for middle-income countries who have a faster rate of CVD burden to prevent high CVD mortality rates that might hamper their economic growth